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Efficacy of the additional use of subgingival air polishing with erythritol powder in the treatment of periodontitis patients: a randomized controlled clinical trial

Mensi M, Scotti E, Sordillo A, Calza S, Guarnelli ME, Fabbri C, Farina R, Trombelli L

Clinical Oral Investigations (2021)

Abstract

Objectives: To date, scarce evidence exists around the application of subgingival air polishing during treatment of severe periodontitis. The aim of this study was to evaluate the benefits of subgingival air polishing during non-surgical treatment of deep bleeding pockets in stages III–IV periodontitis patients. Materials and methods: Forty patients with stages III–IV periodontitis were selected, and pockets with probing depth (PD) 5–9 mm and bleeding on probing (BoP) were selected as experimental sites. All patients underwent a full-mouth session of erythritol powder supragingival air polishing and ultrasonic instrumentation. Test group received additional subgingival air polishing at experimental sites. The proportion of experimental sites shifting to PD ≤ 4 mm and no BoP at 3 months (i.e., non-bleeding closed pockets, NBCPs) was regarded as the primary outcome variable. Results: The proportion of NBCP was comparable between test and control group (47.9 and 44.7%, respectively). Baseline PD of 7–9 mm, multi-rooted teeth and the presence of plaque negatively influenced the probability of obtaining NBCP. Conclusions: The additional application of subgingival air polishing does not seem to provide any significant clinical advantage in achieving closure at moderate to deep bleeding pockets in treatment of stages III–IV periodontitis patients.

Keywords

non-surgical periodontal therapyclinical trialplaque controlperiodontitisair polishingerythritolguided biofilm therapysubgingival debridement

Citazione

Mensi M, Scotti E, Sordillo A, Calza S, Guarnelli ME, Fabbri C, Farina R, Trombelli L. Efficacy of the additional use of subgingival air polishing with erythritol powder in the treatment of periodontitis patients: a randomized controlled clinical trial. Clinical Oral Investigations. 2021. doi: 10.1007/s00784-020-03648-z

Study Highlights

This RCT (Part I of a two-part study) evaluated clinical outcomes of subgingival air-polishing with erythritol+CHX powder in stage III–IV periodontitis (n=40, 20/group).

Primary outcome (NBCP at 3 months):

  • Test group: 47.9%
  • Control group: 44.7%
  • No significant difference (p=0.64)

Overall pocket closure (PD ≤4mm regardless of BoP):

  • Test: 80%
  • Control: 77.6%

Factors negatively affecting NBCP:

  • Baseline PD 7–9 mm vs 5–6 mm (OR 0.30, p<0.001)
  • Multi-rooted teeth (OR 0.66, p=0.002)
  • Presence of plaque at T1 (OR 0.66, p=0.001)

Notable finding: Test protocol showed potential advantage at multi-rooted teeth with PD 5–6 mm (56.4% vs 40.8% NBCP), though not statistically significant.

Clinical relevance: While full-mouth air polishing + ultrasonic debridement is effective (~80% pocket closure), the additional subgingival air-polishing step provides no significant clinical benefit over ultrasonic instrumentation alone for deep bleeding pockets.